Under the background of “the silk road economic belt” initiative,regional tourism cooperation has become an important focus in the sub-regional economic cooperation.This paper conceiving Sino-Kazakhstan Khorgosinternational border cooperation center as the carrier,proposes the construction of the Sino-Kazakhstan cross-border tourism cooperation zone in the Ili prefecture,Xinjiang,China and Almaty, Kazakhstan, adjacent to of Xinjiang and demonstrates its feasibility.This paper selects the two countries’ foreign exchange earnings, foreign exchange expenditure and GDP per capita indicators, anduses the grey prediction model to predict its market potential.The results show that the cross-border tourism market potential is tremendous, and has the basis of the construction of Sino-Kazakhstan cross-border tourism cooperation zone. Therefore, this paperconceives the “three-step” strategy of Sino-Kazakhstan cross-border tourism cooperation zone, and proposes the overall plan of the Sino-Kazakhstan cross-border tourism cooperation zone from aspects of the framework agreement, organization, fund and so on, looking forward to providing the reference to the construction of Sino-Kazakhstan cross-border tourism cooperation zone in the future.