Central Asian countries including Kyrgyzstan are the core area in constructing the Silk Road Economic belt. The bilateral trade volume between China and Kyrgyzstan has increased about 150 times since the two countries established the diplomatic relationship in 1992. China has become the second largest investment country and trade partner of Kyrgyzstan. Kyrgyzstan has become the center of transit trade and distribution for China's commodity.The essay divides the history of economic and trade cooperation between China and Kyrgyzstan into three stages,i.e.initial and tortuous stage of development, period of rapid growth, stage of comprehensive cooperation. The paper summarizes the results and characteristics of each stage.Kyrgyzstan has joined Eurasian Economic Union in 2015, which will bring new challenge for China. In the joint construction of the “the Silk Road Economic Belt”, there is good prospect of economic and trade cooperation between China and Kyrgyzstan.